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Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis
INTRODUCTION: Osteoarthritis (OA) is a common joint disease that can cause gradual disability among the aging population. Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a key transcription factor that regulates the expression of phase II antioxidant enzymes that provide protection against oxi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583998/ https://www.ncbi.nlm.nih.gov/pubmed/26408027 http://dx.doi.org/10.1186/s13075-015-0774-3 |