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Integrative genomics analysis of genes with biallelic loss and its relation to the expression of mRNA and micro-RNA in esophageal squamous cell carcinoma

BACKGROUND: Genomic instability plays an important role in human cancers. We previously characterized genomic instability in esophageal squamous cell carcinomas (ESCC) in terms of loss of heterozygosity (LOH) and copy number (CN) changes in tumors. In the current study we focus on biallelic loss and...

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Detalles Bibliográficos
Autores principales: Hu, Nan, Wang, Chaoyu, Clifford, Robert J., Yang, Howard H., Su, Hua, Wang, Lemin, Wang, Yuan, Xu, Yi, Tang, Ze-Zhong, Ding, Ti, Zhang, Tongwu, Goldstein, Alisa M., Giffen, Carol, Lee, Maxwell P., Taylor, Philip R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584010/
https://www.ncbi.nlm.nih.gov/pubmed/26409826
http://dx.doi.org/10.1186/s12864-015-1919-0