The Fine LINE: Methylation Drawing the Cancer Landscape

LINE-1 (L1) is the most abundant mammalian transposable element that comprises nearly 20% of the genome, and nearly half of the mammalian genome has stemmed from L1-mediated mobilization. Expression and retrotransposition of L1 are suppressed by complex mechanisms, where the key role belongs to DNA...

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Detalles Bibliográficos
Autores principales: Miousse, Isabelle R., Koturbash, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584040/
https://www.ncbi.nlm.nih.gov/pubmed/26448926
http://dx.doi.org/10.1155/2015/131547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584040/
https://www.ncbi.nlm.nih.gov/pubmed/26448926
http://dx.doi.org/10.1155/2015/131547

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