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PKA Inhibitor H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulfonamide) Attenuates Synaptic Dysfunction and Neuronal Cell Death following Ischemic Injury

The cyclic AMP-dependent protein kinase (PKA), which activates prosurvival signaling proteins, has been implicated in the expression of long-term potentiation and hippocampal long-term memory. It has come to light that H89 commonly known as the PKA inhibitor have diverse roles in the nervous system...

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Detalles Bibliográficos
Autores principales: Song, Juhyun, Cheon, So Yeong, Lee, Won Taek, Park, Kyung Ah, Lee, Jong Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584069/
https://www.ncbi.nlm.nih.gov/pubmed/26448879
http://dx.doi.org/10.1155/2015/374520