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Long Noncoding RNAs as New Architects in Cancer Epigenetics, Prognostic Biomarkers, and Potential Therapeutic Targets

Recent advances in genome-wide analysis have revealed that 66% of the genome is actively transcribed into noncoding RNAs (ncRNAs) while less than 2% of the sequences encode proteins. Among ncRNAs, high-resolution microarray and massively parallel sequencing technologies have identified long ncRNAs (...

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Detalles Bibliográficos
Autores principales: Meseure, Didier, Drak Alsibai, Kinan, Nicolas, Andre, Bieche, Ivan, Morillon, Antonin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584070/
https://www.ncbi.nlm.nih.gov/pubmed/26448935
http://dx.doi.org/10.1155/2015/320214