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Mathematical Model of Innate and Adaptive Immunity of Sepsis: A Modeling and Simulation Study of Infectious Disease

Sepsis is a systemic inflammatory response (SIR) to infection. In this work, a system dynamics mathematical model (SDMM) is examined to describe the basic components of SIR and sepsis progression. Both innate and adaptive immunities are included, and simulated results in silico have shown that adapt...

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Detalles Bibliográficos
Autores principales: Shi, Zhenzhen, Wu, Chih-Hang J., Ben-Arieh, David, Simpson, Steven Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584099/
https://www.ncbi.nlm.nih.gov/pubmed/26446682
http://dx.doi.org/10.1155/2015/504259