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Protective Effect of Triptolide against Glomerular Mesangial Cell Proliferation and Glomerular Fibrosis in Rats Involves the TGF-β1/Smad Signaling Pathway

Triptolide as a main active ingredient of Tripterygium wilfordii is known to be exerting anti-inflammatory, marked immunosuppressive, and podocyte-protective effects. In this study, we investigated the protective effect of triptolide in kidney disease. Rat glomerular mesangial cells were randomly di...

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Detalles Bibliográficos
Autores principales: Cao, Yingjie, Huang, Xinzhong, Fan, Yaping, Chen, Xiaolan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584226/
https://www.ncbi.nlm.nih.gov/pubmed/26451157
http://dx.doi.org/10.1155/2015/814089