Cargando…
Protective Effect of Triptolide against Glomerular Mesangial Cell Proliferation and Glomerular Fibrosis in Rats Involves the TGF-β1/Smad Signaling Pathway
Triptolide as a main active ingredient of Tripterygium wilfordii is known to be exerting anti-inflammatory, marked immunosuppressive, and podocyte-protective effects. In this study, we investigated the protective effect of triptolide in kidney disease. Rat glomerular mesangial cells were randomly di...
Autores principales: | Cao, Yingjie, Huang, Xinzhong, Fan, Yaping, Chen, Xiaolan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584226/ https://www.ncbi.nlm.nih.gov/pubmed/26451157 http://dx.doi.org/10.1155/2015/814089 |
Ejemplares similares
-
Effects of bradykinin on proliferation, apoptosis, and cycle of glomerular mesangial cells via the TGF-β1/Smad signaling pathway
por: DONG, Ji, et al.
Publicado: (2021) -
Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway
por: Han, Fei, et al.
Publicado: (2017) -
Triptolide Suppresses Glomerular Mesangial Cell Proliferation in Diabetic Nephropathy Is Associated with Inhibition of PDK1/Akt/mTOR Pathway: Erratum
por: Han, Fei, et al.
Publicado: (2020) -
BAFF is involved in the pathogenesis of IgA nephropathy by activating the TRAF6/NF-κB signaling pathway in glomerular mesangial cells
por: Cao, Yingjie, et al.
Publicado: (2020) -
Corosolic acid inhibits the proliferation of glomerular mesangial cells and protects against diabetic renal damage
por: Li, Xiao-Qiang, et al.
Publicado: (2016)