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Neutrophils Do Not Express IL-17A in the Context of Acute Oropharyngeal Candidiasis

IL-17 protects against pathogens by acting on nonhematopoietic cells to induce neutrophil recruitment through upregulation of chemokines and G-CSF. IL-17- and Th17-deficient humans and mice are susceptible to mucosal Candida albicans infections, linked to impaired neutrophil responses. IL-17 product...

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Detalles Bibliográficos
Autores principales: Huppler, Anna R., Verma, Akash H., Conti, Heather R., Gaffen, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584272/
https://www.ncbi.nlm.nih.gov/pubmed/26213975
http://dx.doi.org/10.3390/pathogens4030559