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Penetration of HIV-1 Tat(47–57) into PC/PE Bilayers Assessed by MD Simulation and X-ray Scattering

The interactions of the basic, cell-penetrating region (Y(47)GRKKRRQRRR(57)) of the HIV-1 Tat protein with dioleoylphosphatidylcholine (DOPC) bilayers were previously assessed by comparing experimental X-ray diffuse scattering with atomistic molecular dynamics simulations. Here, we extend this inves...

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Detalles Bibliográficos
Autores principales: Neale, Chris, Huang, Kun, García, Angel E., Tristram-Nagle, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584291/
https://www.ncbi.nlm.nih.gov/pubmed/26402709
http://dx.doi.org/10.3390/membranes5030473