Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1

The mechanism of antibody-mediated protection is a major focus of HIV-1 vaccine development and a significant issue in the control of viremia. Virus neutralization, Fc-mediated effector function, or both, are major mechanisms of antibody-mediated protection against HIV-1, although other mechanisms,...

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Detalles Bibliográficos
Autores principales: Lewis, George K., Finzi, Andrés, DeVico, Anthony L., Pazgier, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584300/
https://www.ncbi.nlm.nih.gov/pubmed/26393642
http://dx.doi.org/10.3390/v7092856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584300/
https://www.ncbi.nlm.nih.gov/pubmed/26393642
http://dx.doi.org/10.3390/v7092856

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