Genetic Diversity and Selective Pressure in Hepatitis C Virus Genotypes 1–6: Significance for Direct-Acting Antiviral Treatment and Drug Resistance

Treatment with pan-genotypic direct-acting antivirals, targeting different viral proteins, is the best option for clearing hepatitis C virus (HCV) infection in chronically infected patients. However, the diversity of the HCV genome is a major obstacle for the development of antiviral drugs, vaccines...

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Detalles Bibliográficos
Autores principales: Cuypers, Lize, Li, Guangdi, Libin, Pieter, Piampongsant, Supinya, Vandamme, Anne-Mieke, Theys, Kristof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584301/
https://www.ncbi.nlm.nih.gov/pubmed/26389941
http://dx.doi.org/10.3390/v7092857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584301/
https://www.ncbi.nlm.nih.gov/pubmed/26389941
http://dx.doi.org/10.3390/v7092857

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