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Replication Stress: A Lifetime of Epigenetic Change

DNA replication is essential for cell division. Challenges to the progression of DNA polymerase can result in replication stress, promoting the stalling and ultimately collapse of replication forks. The latter involves the formation of DNA double-strand breaks (DSBs) and has been linked to both geno...

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Detalles Bibliográficos
Autores principales: Khurana, Simran, Oberdoerffer, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584333/
https://www.ncbi.nlm.nih.gov/pubmed/26378584
http://dx.doi.org/10.3390/genes6030858