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Replication Stress: A Lifetime of Epigenetic Change
DNA replication is essential for cell division. Challenges to the progression of DNA polymerase can result in replication stress, promoting the stalling and ultimately collapse of replication forks. The latter involves the formation of DNA double-strand breaks (DSBs) and has been linked to both geno...
Autores principales: | Khurana, Simran, Oberdoerffer, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584333/ https://www.ncbi.nlm.nih.gov/pubmed/26378584 http://dx.doi.org/10.3390/genes6030858 |
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