Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer

Altered DNA methylation patterns are found in many diseases, particularly in cancer, where the analysis of DNA methylation holds the promise to provide diagnostic, prognostic and predictive information of great clinical value. Methylation of the promoter-associated CpG island of GSTP1 occurs in many...

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Detalles Bibliográficos
Autores principales: Grenaker Alnaes, Grethe I., Ronneberg, Jo Anders, Kristensen, Vessela N., Tost, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584334/
https://www.ncbi.nlm.nih.gov/pubmed/26393654
http://dx.doi.org/10.3390/genes6030878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584334/
https://www.ncbi.nlm.nih.gov/pubmed/26393654
http://dx.doi.org/10.3390/genes6030878

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