Inclusion of homologous DNA in nuclease-mediated gene targeting facilitates a higher incidence of bi-allelically modified cells

BACKGROUND: Recent advancements in gene editing techniques have increased in number and utility. These techniques are an attractive alternative to conventional gene targeting methods via homologous recombination due to the ease of use and the high efficiency of gene editing. We have previously produ...

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Detalles Bibliográficos
Autores principales: Beaton, Benjamin P, Kwon, Deug-Nam, Choi, Yun-Jung, Kim, Jae-Hwan, Samuel, Melissa S, Benne, Joshua A, Wells, Kevin D, Lee, Kiho, Kim, Jin-Hoi, Prather, Randall S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584494/
https://www.ncbi.nlm.nih.gov/pubmed/26381494
http://dx.doi.org/10.1111/xen.12194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584494/
https://www.ncbi.nlm.nih.gov/pubmed/26381494
http://dx.doi.org/10.1111/xen.12194

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