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Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways

The molecular basis of cancer and cancer multiple phenotypes are not yet fully understood. Next Generation Sequencing promises new insight into the role of genetic interactions in shaping the complexity of cancer. Aiming to outline the differences in mutation patterns between familial colorectal can...

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Detalles Bibliográficos
Autores principales: Suleiman, Suleiman H., Koko, Mahmoud E., Nasir, Wafaa H., Elfateh, Ommnyiah, Elgizouli, Ubai K., Abdallah, Mohammed O. E., Alfarouk, Khalid O., Hussain, Ayman, Faisal, Shima, Ibrahim, Fathelrahamn M. A., Romano, Maurizio, Sultan, Ali, Banks, Lawrence, Newport, Melanie, Baralle, Francesco, Elhassan, Ahmed M., Mohamed, Hiba S., Ibrahim, Muntaser E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584935/
https://www.ncbi.nlm.nih.gov/pubmed/26442106
http://dx.doi.org/10.3389/fgene.2015.00288