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Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective
Multi-target drugs have raised considerable interest in the last decade owing to their advantages in the treatment of complex diseases and health conditions linked to drug resistance issues. Prospective drug repositioning to treat comorbid conditions is an additional, overlooked application of multi...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585027/ https://www.ncbi.nlm.nih.gov/pubmed/26441661 http://dx.doi.org/10.3389/fphar.2015.00205 |