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Therapeutic Potential of Hyporesponsive CD4(+) T Cells in Autoimmunity

The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs induce tolerance through T-cell deletion, generation of regulatory T cells, and/or induction of T-cell anergy. Anergy is defined as an unresponsive state...

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Detalles Bibliográficos
Autores principales: Maggi, Jaxaira, Schafer, Carolina, Ubilla-Olguín, Gabriela, Catalán, Diego, Schinnerling, Katina, Aguillón, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585084/
https://www.ncbi.nlm.nih.gov/pubmed/26441992
http://dx.doi.org/10.3389/fimmu.2015.00488