A multiscale computational model of spatially resolved calcium cycling in cardiac myocytes: from detailed cleft dynamics to the whole cell concentration profiles

Mathematical modeling of excitation-contraction coupling (ECC) in ventricular cardiac myocytes is a multiscale problem, and it is therefore difficult to develop spatially detailed simulation tools. ECC involves gradients on the length scale of 100 nm in dyadic spaces and concentration profiles along...

Descripción completa

Detalles Bibliográficos
Autores principales: Vierheller, Janine, Neubert, Wilhelm, Falcke, Martin, Gilbert, Stephen H., Chamakuri, Nagaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Physics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585174/
https://www.ncbi.nlm.nih.gov/pubmed/26441674
http://dx.doi.org/10.3389/fphys.2015.00255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585174/
https://www.ncbi.nlm.nih.gov/pubmed/26441674
http://dx.doi.org/10.3389/fphys.2015.00255

Ejemplares similares