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FOXP3(+) Treg Cells and Gender Bias in Autoimmune Diseases

CD4(+)CD25(+) regulatory T (Treg) cells play a pivotal role in the maintenance of immune homeostasis, where the X-linked master transcription factor forkhead box P3 (FOXP3) determines Treg cell development and function. Genetic deficiency of foxp3 induces dysfunction of Treg cells and immuno-dysregu...

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Detalles Bibliográficos
Autores principales: Nie, Jia, Li, Yang Yang, Zheng, Song Guo, Tsun, Andy, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585344/
https://www.ncbi.nlm.nih.gov/pubmed/26441996
http://dx.doi.org/10.3389/fimmu.2015.00493