mTOR activates the VPS34–UVRAG complex to regulate autolysosomal tubulation and cell survival

Lysosomes are essential organelles that function to degrade and recycle unwanted, damaged and toxic biological components. Lysosomes also act as signalling platforms in activating the nutrient-sensing kinase mTOR. mTOR regulates cellular growth, but it also helps to maintain lysosome identity by ini...

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Detalles Bibliográficos
Autores principales: Munson, Michael J, Allen, George FG, Toth, Rachel, Campbell, David G, Lucocq, John M, Ganley, Ian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585463/
https://www.ncbi.nlm.nih.gov/pubmed/26139536
http://dx.doi.org/10.15252/embj.201590992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585463/
https://www.ncbi.nlm.nih.gov/pubmed/26139536
http://dx.doi.org/10.15252/embj.201590992

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