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A Single-Center, Open-Label, 3-Way Crossover Trial to Determine the Pharmacokinetic and Pharmacodynamic Interaction Between Nebivolol and Valsartan in Healthy Volunteers at Steady State

Combining different classes of antihypertensives is more effective for reducing blood pressure (BP) than increasing the dose of monotherapies. The aims of this phase I study were to investigate pharmacokinetic and pharmacodynamic interactions between nebivolol, a vasodilatory β(1)-selective blocker,...

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Detalles Bibliográficos
Autores principales: Chen, Chun Lin, Desai-Krieger, Daksha, Ortiz, Stephan, Kerolous, Majid, Wright, Harold M., Ghahramani, Parviz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal of Therapeutics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585485/
https://www.ncbi.nlm.nih.gov/pubmed/25853236
http://dx.doi.org/10.1097/MJT.0000000000000247