Cargando…

Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II(−/−) Mouse

Idiopathic epilepsies have frequently been linked to mutations in voltage-gated channels (channelopathies); recently, mutations in several genes encoding presynaptic proteins have been shown to cause epilepsy in humans and mice, indicating that epilepsy can also be considered a synaptopathy. However...

Descripción completa

Detalles Bibliográficos
Autores principales: Medrihan, Lucian, Ferrea, Enrico, Greco, Barbara, Baldelli, Pietro, Benfenati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585492/
https://www.ncbi.nlm.nih.gov/pubmed/24962993
http://dx.doi.org/10.1093/cercor/bhu141