Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment

Diabetes mellitus is characterized by disrupted glucose homeostasis due to loss or dysfunction of insulin-producing beta cells. In this work, we characterize pancreatic islet development and function in zebrafish mutant for pdx1, a gene which in humans is linked to genetic forms of diabetes and is a...

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Detalles Bibliográficos
Autores principales: Kimmel, Robin A., Dobler, Stefan, Schmitner, Nicole, Walsen, Tanja, Freudenblum, Julia, Meyer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585597/
https://www.ncbi.nlm.nih.gov/pubmed/26384018
http://dx.doi.org/10.1038/srep14241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585597/
https://www.ncbi.nlm.nih.gov/pubmed/26384018
http://dx.doi.org/10.1038/srep14241

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