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Highly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigs

Transgenic pigs play an important role in producing higher quality food in agriculture and improving human health when used as animal models for various human diseases in biomedicine. Production of transgenic pigs, however, is a lengthy and inefficient process that hinders research using pig models....

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Detalles Bibliográficos
Autores principales: Ruan, Jinxue, Li, Hegang, Xu, Kui, Wu, Tianwen, Wei, Jingliang, Zhou, Rong, Liu, Zhiguo, Mu, Yulian, Yang, Shulin, Ouyang, Hongsheng, Yanru Chen-Tsai, Ruby, Li, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585612/
https://www.ncbi.nlm.nih.gov/pubmed/26381350
http://dx.doi.org/10.1038/srep14253