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Highly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigs
Transgenic pigs play an important role in producing higher quality food in agriculture and improving human health when used as animal models for various human diseases in biomedicine. Production of transgenic pigs, however, is a lengthy and inefficient process that hinders research using pig models....
Autores principales: | Ruan, Jinxue, Li, Hegang, Xu, Kui, Wu, Tianwen, Wei, Jingliang, Zhou, Rong, Liu, Zhiguo, Mu, Yulian, Yang, Shulin, Ouyang, Hongsheng, Yanru Chen-Tsai, Ruby, Li, Kui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585612/ https://www.ncbi.nlm.nih.gov/pubmed/26381350 http://dx.doi.org/10.1038/srep14253 |
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