Φ-score: A cell-to-cell phenotypic scoring method for sensitive and selective hit discovery in cell-based assays

Phenotypic screening monitors phenotypic changes induced by perturbations, including those generated by drugs or RNA interference. Currently-used methods for scoring screen hits have proven to be problematic, particularly when applied to physiologically relevant conditions such as low cell numbers o...

Descripción completa

Detalles Bibliográficos
Autores principales: Guyon, Laurent, Lajaunie, Christian, fer, Frédéric, bhajun, Ricky, sulpice, Eric, pinna, Guillaume, campalans, Anna, radicella, J. Pablo, rouillier, Philippe, mary, Mélissa, combe, Stéphanie, obeid, Patricia, vert, Jean-Philippe, gidrol, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585642/
https://www.ncbi.nlm.nih.gov/pubmed/26382112
http://dx.doi.org/10.1038/srep14221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585642/
https://www.ncbi.nlm.nih.gov/pubmed/26382112
http://dx.doi.org/10.1038/srep14221

Ejemplares similares