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Φ-score: A cell-to-cell phenotypic scoring method for sensitive and selective hit discovery in cell-based assays

Phenotypic screening monitors phenotypic changes induced by perturbations, including those generated by drugs or RNA interference. Currently-used methods for scoring screen hits have proven to be problematic, particularly when applied to physiologically relevant conditions such as low cell numbers o...

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Detalles Bibliográficos
Autores principales:	Guyon, Laurent, Lajaunie, Christian, fer, Frédéric, bhajun, Ricky, sulpice, Eric, pinna, Guillaume, campalans, Anna, radicella, J. Pablo, rouillier, Philippe, mary, Mélissa, combe, Stéphanie, obeid, Patricia, vert, Jean-Philippe, gidrol, Xavier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585642/ https://www.ncbi.nlm.nih.gov/pubmed/26382112 http://dx.doi.org/10.1038/srep14221

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