RTB Lectin: a novel receptor-independent delivery system for lysosomal enzyme replacement therapies

Enzyme replacement therapies have revolutionized patient treatment for multiple rare lysosomal storage diseases but show limited effectiveness for addressing pathologies in “hard-to-treat” organs and tissues including brain and bone. Here we investigate the plant lectin RTB as a novel carrier for hu...

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Detalles Bibliográficos
Autores principales: Acosta, Walter, Ayala, Jorge, Dolan, Maureen C., Cramer, Carole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585660/
https://www.ncbi.nlm.nih.gov/pubmed/26382970
http://dx.doi.org/10.1038/srep14144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585660/
https://www.ncbi.nlm.nih.gov/pubmed/26382970
http://dx.doi.org/10.1038/srep14144

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