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RTB Lectin: a novel receptor-independent delivery system for lysosomal enzyme replacement therapies
Enzyme replacement therapies have revolutionized patient treatment for multiple rare lysosomal storage diseases but show limited effectiveness for addressing pathologies in “hard-to-treat” organs and tissues including brain and bone. Here we investigate the plant lectin RTB as a novel carrier for hu...
Autores principales: | Acosta, Walter, Ayala, Jorge, Dolan, Maureen C., Cramer, Carole L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585660/ https://www.ncbi.nlm.nih.gov/pubmed/26382970 http://dx.doi.org/10.1038/srep14144 |
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