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TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation

Endothelial cell proliferation is a critical event during angiogenesis, regulated by both soluble factors and mechanical forces. Although the proliferation of tumor cells is studied extensively, little is known about the proliferation of tumor endothelial cells (TEC) and its contribution to tumor an...

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Detalles Bibliográficos
Autores principales: Thoppil, Roslin J., Adapala, Ravi K., Cappelli, Holly C., Kondeti, Vinay, Dudley, Andrew C., Gary Meszaros, J., Paruchuri, Sailaja, Thodeti, Charles K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585691/
https://www.ncbi.nlm.nih.gov/pubmed/26388427
http://dx.doi.org/10.1038/srep14257