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Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase

It has been reported that the Numb protein is methylated at lysine 158 and 163 and that this methylation is introduced by the SET8 protein lysine methyltransferase [Dhami et al., (2013) Molecular Cell 50, 565–576]. We studied this methylation in vitro using peptide arrays and recombinant Numb protei...

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Detalles Bibliográficos
Autores principales: Weirich, Sara, Kusevic, Denis, Kudithipudi, Srikanth, Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585732/
https://www.ncbi.nlm.nih.gov/pubmed/26391684
http://dx.doi.org/10.1038/srep13813