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Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase
It has been reported that the Numb protein is methylated at lysine 158 and 163 and that this methylation is introduced by the SET8 protein lysine methyltransferase [Dhami et al., (2013) Molecular Cell 50, 565–576]. We studied this methylation in vitro using peptide arrays and recombinant Numb protei...
Autores principales: | Weirich, Sara, Kusevic, Denis, Kudithipudi, Srikanth, Jeltsch, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585732/ https://www.ncbi.nlm.nih.gov/pubmed/26391684 http://dx.doi.org/10.1038/srep13813 |
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