Tumour-promoting role of SOCS1 in colorectal cancer cells

The SOCS1 (Suppressor Of Cytokine Signalling 1) protein is considered a tumour suppressor. Notably, the SOCS1 gene is frequently silenced in cancer by hypermethylation of its promoter. Besides blocking inflammation, SOCS1 tumour suppressor activity involves Met receptor inhibition and enhancement of...

Descripción completa

Detalles Bibliográficos
Autores principales: Tobelaim, William S., Beaurivage, Claudia, Champagne, Audrey, Pomerleau, Véronique, Simoneau, Aline, Chababi, Walid, Yeganeh, Mehdi, Thibault, Philippe, Klinck, Roscoe, Carrier, Julie C., Ferbeyre, Gerardo, Ilangumaran, Subburaj, Saucier, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585755/
https://www.ncbi.nlm.nih.gov/pubmed/26391193
http://dx.doi.org/10.1038/srep14301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585755/
https://www.ncbi.nlm.nih.gov/pubmed/26391193
http://dx.doi.org/10.1038/srep14301

Ejemplares similares