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Tumour-promoting role of SOCS1 in colorectal cancer cells

The SOCS1 (Suppressor Of Cytokine Signalling 1) protein is considered a tumour suppressor. Notably, the SOCS1 gene is frequently silenced in cancer by hypermethylation of its promoter. Besides blocking inflammation, SOCS1 tumour suppressor activity involves Met receptor inhibition and enhancement of...

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Detalles Bibliográficos
Autores principales:	Tobelaim, William S., Beaurivage, Claudia, Champagne, Audrey, Pomerleau, Véronique, Simoneau, Aline, Chababi, Walid, Yeganeh, Mehdi, Thibault, Philippe, Klinck, Roscoe, Carrier, Julie C., Ferbeyre, Gerardo, Ilangumaran, Subburaj, Saucier, Caroline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585755/ https://www.ncbi.nlm.nih.gov/pubmed/26391193 http://dx.doi.org/10.1038/srep14301

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