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Genome-wide homozygosity signature and risk of Hodgkin lymphoma

Recent studies have reported that regions of homozygosity (ROH) in the genome are detectable in outbred populations and can be associated with an increased risk of malignancy. To examine whether homozygosity is associated with an increased risk of developing Hodgkin lymphoma (HL) we analysed 589 HL...

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Detalles Bibliográficos
Autores principales: Sud, Amit, Cooke, Rosie, Swerdlow, Anthony J., Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585760/
https://www.ncbi.nlm.nih.gov/pubmed/26391888
http://dx.doi.org/10.1038/srep14315