Expression profile of a Caenorhabditis elegans model of adult neuronal ceroid lipofuscinosis reveals down regulation of ubiquitin E3 ligase components

Cysteine string protein (CSP) is a chaperone of the Dnaj/Hsp40 family of proteins and is essential for synaptic maintenance. Mutations in the human gene encoding CSP, DNAJC5, cause adult neuronal ceroid lipofucinosis (ANCL) which is characterised by progressive dementia, movement disorders, seizures...

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Detalles Bibliográficos
Autores principales: McCue, Hannah V., Chen, Xi, Barclay, Jeff W., Morgan, Alan, Burgoyne, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585785/
https://www.ncbi.nlm.nih.gov/pubmed/26395859
http://dx.doi.org/10.1038/srep14392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585785/
https://www.ncbi.nlm.nih.gov/pubmed/26395859
http://dx.doi.org/10.1038/srep14392

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