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Enterovirus 71 2C Protein Inhibits NF-κB Activation by Binding to RelA(p65)

Viruses evolve multiple ways to interfere with NF-κB signaling, a key regulator of innate and adaptive immunity. Enterovirus 71 (EV71) is one of primary pathogens that cause hand-foot-mouth disease. Here, we identify RelA(p65) as a novel binding partner for EV71 2C protein from yeast two-hybrid scre...

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Detalles Bibliográficos
Autores principales: Du, Haiwei, Yin, Peiqi, Yang, Xiaojie, Zhang, Leiliang, Jin, Qi, Zhu, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585786/
https://www.ncbi.nlm.nih.gov/pubmed/26394554
http://dx.doi.org/10.1038/srep14302