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Raster image cross-correlation analysis for spatiotemporal visualization of intracellular degradation activities against exogenous DNAs

Reducing intracellular DNA degradation is critical to enhance the efficiency of gene therapy. Exogenous DNA incorporation into cells is strictly blocked by the defense machinery of intracellular nuclease activity. Raster image correlation spectroscopy (RICS) and raster image cross-correlation spectr...

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Detalles Bibliográficos
Autores principales: Sasaki, Akira, Yamamoto, Johtaro, Jin, Takashi, Kinjo, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585853/
https://www.ncbi.nlm.nih.gov/pubmed/26400011
http://dx.doi.org/10.1038/srep14428