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A mouse model replicating hippocampal sparing cranial irradiation in humans: A tool for identifying new strategies to limit neurocognitive decline

Cancer patients undergoing cranial irradiation are at risk of developing neurocognitive impairments. Recent evidence suggests that radiation-induced injury to the hippocampi could play an important role in this cognitive decline. As a tool for studying the mechanisms of hippocampal-dependent cogniti...

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Detalles Bibliográficos
Autores principales: Tomé, Wolfgang A., Gökhan, Şölen, Brodin, N. Patrik, Gulinello, Maria E., Heard, John, Mehler, Mark F., Guha, Chandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585869/
https://www.ncbi.nlm.nih.gov/pubmed/26399509
http://dx.doi.org/10.1038/srep14384