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A mouse model replicating hippocampal sparing cranial irradiation in humans: A tool for identifying new strategies to limit neurocognitive decline
Cancer patients undergoing cranial irradiation are at risk of developing neurocognitive impairments. Recent evidence suggests that radiation-induced injury to the hippocampi could play an important role in this cognitive decline. As a tool for studying the mechanisms of hippocampal-dependent cogniti...
Autores principales: | Tomé, Wolfgang A., Gökhan, Şölen, Brodin, N. Patrik, Gulinello, Maria E., Heard, John, Mehler, Mark F., Guha, Chandan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585869/ https://www.ncbi.nlm.nih.gov/pubmed/26399509 http://dx.doi.org/10.1038/srep14384 |
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