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The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses

Middle East respiratory syndrome coronavirus (MERS-CoV) originated in bats and spread to humans via zoonotic transmission from camels. We analyzed the evolution of the spike (S) gene in betacoronaviruses (betaCoVs) isolated from different mammals, in bat coronavirus populations, as well as in MERS-C...

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Detalles Bibliográficos
Autores principales: Forni, Diego, Filippi, Giulia, Cagliani, Rachele, De Gioia, Luca, Pozzoli, Uberto, Al-Daghri, Nasser, Clerici, Mario, Sironi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585914/
https://www.ncbi.nlm.nih.gov/pubmed/26404138
http://dx.doi.org/10.1038/srep14480