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Recombinant human endostatin enhances the radioresponse in esophageal squamous cell carcinoma by normalizing tumor vasculature and reducing hypoxia

The aim of this study was to investigate the effect of recombinant human endostatin (rh-Endo) in combination with radiation therapy (RT) on esophageal squamous cell carcinoma (ESCC) and explore the potential mechanisms. ECA109-bearing nude mice were administered RT and/or rh-Endo treatment. Tumor vo...

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Detalles Bibliográficos
Autores principales: Zhu, Hongcheng, Yang, Xi, Ding, Yuqiong, Liu, Jia, Lu, Jing, Zhan, Liangliang, Qin, Qin, Zhang, Hao, Chen, Xiaochen, Yang, Yuehua, Yang, Yan, Liu, Zheming, Yang, Meiling, Zhou, Xifa, Cheng, Hongyan, Sun, Xinchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585975/
https://www.ncbi.nlm.nih.gov/pubmed/26412785
http://dx.doi.org/10.1038/srep14503