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Expression of IL-37 contributes to the immunosuppressive property of human CD4(+)CD25(+) regulatory T cells

Interleukin-37 (IL-37) possesses the function of down-regulate systemic and local inflammation. It is unknown whether IL-37 is expressed in human regulatory T cells (Tregs) and its role in modulating the immune response of Tregs. In the present study, cell surface molecules and secretory cytokines w...

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Detalles Bibliográficos
Autores principales: Shuai, Xu, Wei-min, Li, Tong, Ya-lin, Dong, Ning, Sheng, Zhi-yong, Yao, Yong-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4585986/
https://www.ncbi.nlm.nih.gov/pubmed/26411375
http://dx.doi.org/10.1038/srep14478