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Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2

Reducing the expression of the Indy (Acronym for ‘I'm Not Dead, Yet’) gene in lower organisms promotes longevity and leads to a phenotype that resembles various aspects of caloric restriction. In C. elegans, the available data on life span extension is controversial. Therefore, the aim of this...

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Detalles Bibliográficos
Autores principales: Schwarz, Franziska, Karadeniz, Zehra, Fischer-Rosinsky, Antje, Willmes, Diana M., Spranger, Joachim, Birkenfeld, Andreas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586101/
https://www.ncbi.nlm.nih.gov/pubmed/26318988