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Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2
Reducing the expression of the Indy (Acronym for ‘I'm Not Dead, Yet’) gene in lower organisms promotes longevity and leads to a phenotype that resembles various aspects of caloric restriction. In C. elegans, the available data on life span extension is controversial. Therefore, the aim of this...
Autores principales: | Schwarz, Franziska, Karadeniz, Zehra, Fischer-Rosinsky, Antje, Willmes, Diana M., Spranger, Joachim, Birkenfeld, Andreas L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586101/ https://www.ncbi.nlm.nih.gov/pubmed/26318988 |
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