Cargando…

Rescue of failed oocyte activation after ICSI in a mouse model of male factor infertility by recombinant phospholipase Cζ

Artificial oocyte activation to overcome failed fertilization after intracytoplasmic sperm injection (ICSI) in human oocytes typically employs Ca(2+) ionophores to produce a single cytosolic Ca(2+) increase. In contrast, recombinant phospholipase Czeta (PLCζ) causes Ca(2+) oscillations indistinguish...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanusi, Randa, Yu, Yuansong, Nomikos, Michail, Lai, F. Anthony, Swann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586348/
https://www.ncbi.nlm.nih.gov/pubmed/26187950
http://dx.doi.org/10.1093/molehr/gav042