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Nucleosome Repositioning: A Novel Mechanism for Nicotine- and Cocaine-Induced Epigenetic Changes

Drugs of abuse modify behavior by altering gene expression in the brain. Gene expression can be regulated by changes in DNA methylation as well as by histone modifications, which alter chromatin structure, DNA compaction and DNA accessibility. In order to better understand the molecular mechanisms d...

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Detalles Bibliográficos
Autores principales: Brown, Amber N., Vied, Cynthia, Dennis, Jonathan H., Bhide, Pradeep G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586372/
https://www.ncbi.nlm.nih.gov/pubmed/26414157
http://dx.doi.org/10.1371/journal.pone.0139103