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Excess Secretion of Gel-Forming Mucins and Associated Innate Defense Proteins with Defective Mucin Un-Packaging Underpin Gallbladder Mucocele Formation in Dogs

Mucosal protection of the gallbladder is vital yet we know very little about the mechanisms involved. In domestic dogs, an emergent syndrome referred to as gallbladder mucocele formation is characterized by excessive secretion of abnormal mucus that results in obstruction and rupture of the gallblad...

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Detalles Bibliográficos
Autores principales: Kesimer, Mehmet, Cullen, John, Cao, Rui, Radicioni, Giorgia, Mathews, Kyle G., Seiler, Gabriela, Gookin, Jody L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586375/
https://www.ncbi.nlm.nih.gov/pubmed/26414376
http://dx.doi.org/10.1371/journal.pone.0138988